英文名称 |
Anti-AFP Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
AFPD;FETA;HPAFP;HPAFP;alpha 1 Fetoprotein |
稀释比例 |
WB 1:500-2000. IF 1:50-200. |
蛋白分子量 |
69kDa |
Gene ID |
174 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human AFP |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human AFP |
亚细胞定位 |
Secreted |
Swiss Prot |
P02771 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |
应用 |
WB IF |
交叉反应 |
Human Mouse Rat |