| 英文名称 |
Anti-DIABLO Polyclonal Antibody |
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| 宿主 |
Rabbit |
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| 别名 |
DIABLO;DFNA64;SMAC |
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| 稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
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| 蛋白分子量 |
21/22/27kDa |
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| Gene ID |
56616 |
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| 保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
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| 储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
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| 纯化方法 |
Affinity purification |
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| 亚型 |
IgG |
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| 免疫原 |
Recombinant protein of human DIABLO |
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| 亚细胞定位 |
Mitochondrion |
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| Swiss Prot |
Q9NR28 |
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| 克隆类型 |
Polyclonal Antibody |
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| 背景资料 |
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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| 应用 |
WB IHC IF |
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| 交叉反应 |
Human Mouse Rat |
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