| 英文名称 |
Anti-ATIC Monoclonal Antibody |
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| 宿主 |
Mouse |
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| 别名 |
AICAR;AICARFT;HEL-S-70p;IMPCHASE;PURH |
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| 稀释比例 |
WB 1:1000. |
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| 蛋白分子量 |
65kDa |
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| Gene ID |
471 |
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| 保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
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| 储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 纯化方法 |
Affinity purification |
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| 亚型 |
IgG1 |
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| 免疫原 |
Purified recombinant human ATIC protein fragments expressed in E.coli. |
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| 性状 |
液体 |
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| Public Immunogen Range |
Purified recombinant human ATIC protein fragments expressed in E.coli. |
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| 亚细胞定位 |
Cytosol Plasma Membrane |
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| Swiss Prot |
P31939 |
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| 克隆号 |
3H12-C9-H9 |
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| 克隆类型 |
Monoclonal Antibody |
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| 背景资料 |
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. |
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| 应用 |
WB |
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