| 英文名称 |
Anti-ACE Polyclonal Antibody |
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| 宿主 |
Rabbit |
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| 别名 |
ACE1;CD143;DCP;DCP1;Angiotensin Converting Enzyme 1 |
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| 稀释比例 |
WB 1:500-2000. IHC 1:50-100. |
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| 蛋白分子量 |
79/83/132/150kDa |
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| Gene ID |
1636 |
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| 保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
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| 储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 纯化方法 |
Affinity purification |
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| 亚型 |
IgG |
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| 免疫原 |
A synthetic peptide of human ACE |
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| 性状 |
液体 |
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| Public Immunogen Range |
A synthetic peptide of human ACE |
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| 亚细胞定位 |
Cell membrane Cytoplasm Secreted Single-pass type I membrane protein |
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| Swiss Prot |
P12821 |
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| 克隆类型 |
Polyclonal Antibody |
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| 背景资料 |
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. |
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| 应用 |
WB IHC |
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