AIF Mouse Monoclonal Antibody

英文名
试剂别名
产品编号 SK000163M
MDL号
COA MSDS 大包装询盘
产品名称: AIF Mouse Monoclonal Antibody
宿主 Mouse
英文名称 Anti-AIFM1 Monoclonal Antibody
别名 AIF;CMT2D;CMTX4;COWCK;COXPD6;DFNX5;NADMR;NAMSD;PDCD8
稀释比例 WB 1:1000. ICC 1:200.
蛋白分子量 67kDa
Gene ID 9131
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG2a
免疫原 Purified recombinant human AIFM1 protein fragments expressed in E.coli.
性状 液体
亚细胞定位 Cytoplasm Mitochondrion inner membrane Mitochondrion intermembrane space Nucleus perinuclear region
Swiss Prot O95831
克隆号 8H1-B10-A12
克隆类型 Monoclonal Antibody
背景资料 This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
应用    WB IF
交叉反应    Human
危险品级别:
HS符号:
危害声明:

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